Reaction Details Report a problem with these data
Target
Beta-2 adrenergic receptor
Ligand
BDBM50002595
Substrate
n/a
Meas. Tech.
ChEMBL_352720 (CHEMBL863066)
Ki
1585±n/a nM
Citation
Uehling, DE; Shearer, BG; Donaldson, KH; Chao, EY; Deaton, DN; Adkison, KK; Brown, KK; Cariello, NF; Faison, WL; Lancaster, ME; Lin, J; Hart, R; Milliken, TO; Paulik, MA; Sherman, BW; Sugg, EE; Cowan, C Biarylaniline phenethanolamines as potent and selective beta3 adrenergic receptor agonists. J Med Chem 49:2758-71 (2006) [PubMed] Article
More Info.:
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Human
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL