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Target
Glucocorticoid receptor
Ligand
BDBM13775
Substrate
n/a
Meas. Tech.
ChEMBL_1358464 (CHEMBL3281632)
Kd
43±n/a nM
Citation
 El Masry, AH; Braun, VC; Nielsen, CJ; Pratt, WB Synthesis and biological action of two glucocorticoid alkylating agents. J Med Chem 20:1134-9 (1978) [PubMed]  Article 
Target
Name:
Glucocorticoid receptor
Synonyms:
Glucocorticoid receptor | GCR_MOUSE | Nr3c1 | Grl | Grl1 | Glucocorticoid
Type:
Enzyme Catalytic Domain
Mol. Mass.:
86050.26
Organism:
Mouse
Description:
Glucocorticoid 0 MOUSE::P06537
Residue:
783
Sequence:
MDSKESLAPPGRDEVPSSLLGRGRGSVMDLYKTLRGGATVKVSASSPSVAAASQADSKQQRILLDFSKGSASNAQQQQQQQQPQPDLSKAVSLSMGLYMGETETKVMGNDLGYPQQGQLGLSSGETDFRLLEESIANLNRSTSRPENPKSSTPAAGCATPTEKEFPQTHSDPSSEQQNRKSQPGTNGGSVKLYTTDQSTFDILQDLEFSAGSPGKETNESPWRSDLLIDENLLSPLAGEDDPFLLEGDVNEDCKPLILPDTKPKIQDTGDTILSSPSSVALPQVKTEKDDFIELCTPGVIKQEKLGPVYCQASFSGTNIIGNKMSAISVHGVSTSGGQMYHYDMNTASLSQQQDQKPVFNVIPPIPVGSENWNRCQGSGEDNLTSLGAMNFAGRSVFSNGYSSPGMRPDVSSPPSSSSTATGPPPKLCLVCSDEASVCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATAGVSQDTSENANKTIVPAALPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSAWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQASGNLLCFAPDLIINEQRMTLPCMYDQCKHMLFISTELQRLQVSYEEYLCMKTLLLLSSVPKEGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHDVVENLLSYCFQTFLDKSMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK
  
Inhibitor
Name:
BDBM13775
Synonyms:
[3H]cortisol | (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one | cortisol | 3H-cortisol | 11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione | HYDROCORTISONE | US10188667, Example 00023
Type:
Steroid
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: