Reaction Details Report a problem with these data
Target
Carbonic anhydrase
Ligand
BDBM50028010
Substrate
n/a
Meas. Tech.
ChEMBL_1466707 (CHEMBL3404500)
Ki
263±n/a nM
Citation
 Syrjänen, L; Kuuslahti, M; Tolvanen, M; Vullo, D; Parkkila, S; Supuran, CT Theß-carbonic anhydrase from the malaria mosquito Anopheles gambiae is highly inhibited by sulfonamides. Bioorg Med Chem 23:2303-9 (2015) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
Carbonate dehydratase | Carbonic anhydrase
Type:
PROTEIN
Mol. Mass.:
29919.95
Organism:
Anopheles gambiae
Description:
ChEMBL_109570
Residue:
255
Sequence:
MERILRGVMRYRHTTREQMVQEFRKVRDNPQPKAVFFTCMDSRMIPTRFTETHVGDMFVVRNAGNLVPHAEHFQDEYFSCEPAALELGCVVNNIKHIIVCGHSDCKAMNLLYKLKDPEFASLDNRRISPLRAWLCEHANTSLAKFQNLKEIGLDKPLIFSSETPLRKFVAYIDPENNFAIEDKLSQVNTLQQIENVASYGFLKRRLESHDLHIHALWFDIYTGDIYFFSRNSKRFIAIDESSIDRLLDEVRRYYS
  
Inhibitor
Name:
BDBM50028010
Synonyms:
AD-810 | CHEBI:10127 | CI-912 | PD-110843 | Zonegran | Zonisamide
Type:
Small organic molecule
Emp. Form.:
C8H8N2O3S
Mol. Mass.:
212.226
SMILES:
OS(=N)(=O)Cc1noc2ccccc12
Structure:
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