Reaction Details Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50078426
Substrate
n/a
Meas. Tech.
ChEMBL_1471050 (CHEMBL3420495)
EC50
675±n/a nM
Citation
 Petrelli, R; Torquati, I; Kachler, S; Luongo, L; Maione, S; Franchetti, P; Grifantini, M; Novellino, E; Lavecchia, A; Klotz, KN; Cappellacci, L 5'-C-Ethyl-tetrazolyl-N(6)-substituted adenosine and 2-chloro-adenosine derivatives as highly potent dual acting A1 adenosine receptor agonists and A3 adenosine receptor antagonists. J Med Chem 58:2560-6 (2015) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
ADENOSINE A2B | Adenosine receptor A2B (A2B) | AA2BR_HUMAN | ADORA2B | Adenosine receptors; A2a & A2b | Adenosine receptors A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Human
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50078426
Synonyms:
CHEMBL3414940
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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