Target
Arylacetamide deacetylase
Ligand
BDBM50131270
Substrate
n/a
Meas. Tech.
ChEMBL_1481892 (CHEMBL3540583)
Ki
14000±n/a nM
Citation
 Kobayashi, YFukami, TNakajima, AWatanabe, ANakajima, MYokoi, T Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse. Drug Metab Dispos 40:671-9 (2012) [PubMed]  Article 
Target
Name:
Arylacetamide deacetylase
Synonyms:
AAAD_HUMAN | AADAC | Arylacetamide deacetylase | DAC
Type:
PROTEIN
Mol. Mass.:
45743.18
Organism:
Human
Description:
ChEMBL_109673
Residue:
399
Sequence:
MGRKSLYLLIVGILIAYYIYTPLPDNVEEPWRMMWINAHLKTIQNLATFVELLGLHHFMDSFKVVGSFDEVPPTSDENVTVTETKFNNILVRVYVPKRKSEALRRGLFYIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGNLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLFLSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPVESSHLFKFVNWSSLLPERFIKGHVYNNPNYGSSELAKKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTGVQVTHNHVEDGFHGAFSFLGLKISHRLINQYIEWLKENL
  
Inhibitor
Name:
BDBM50131270
Synonyms:
2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide | 4'-nitro-3'-trifluoromethylisobutyranilide | CHEMBL806 | Eulexin | FLUTAMIDE | Niftolide | alpha,alpha,alpha-trifluoro-2-methyl-4'-nitro-m-propionotoluidide | niftolid
Type:
Small organic molecule
Emp. Form.:
C11H11F3N2O3
Mol. Mass.:
276.2118
SMILES:
CC(C)C(=O)Nc1ccc(c(c1)C(F)(F)F)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: