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Target
Formyl peptide receptor-related sequence 1
Ligand
BDBM50097559
Substrate
n/a
Meas. Tech.
ChEMBL_1504350 (CHEMBL3592687)
EC50
2800±n/a nM
Citation
 Lacivita, E; Schepetkin, IA; Stama, ML; Kirpotina, LN; Colabufo, NA; Perrone, R; Khlebnikov, AI; Quinn, MT; Leopoldo, M Novel 3-(1H-indol-3-yl)-2-[3-(4-methoxyphenyl)ureido]propanamides as selective agonists of human formyl-peptide receptor 2. Bioorg Med Chem 23:3913-24 (2015) [PubMed]  Article 
Target
Name:
Formyl peptide receptor-related sequence 1
Synonyms:
FMLP-R-I | FMLP-related receptor I | FPRS1_MOUSE | Formyl peptide receptor related sequence 1 | Formyl peptide receptor-like 1 | Fpr-s1 | Fpr2 | Fpr3 | Fprl1 | LXA4 receptor | Lipoxin A4 receptor | Lxa4r | N-formyl peptide receptor 2 | N-formyl peptide receptor 3
Type:
PROTEIN
Mol. Mass.:
39532.25
Organism:
Mus musculus
Description:
ChEMBL_109574
Residue:
351
Sequence:
METNYSIPLNGSDVVIYDSTISRVLWILSMVVVSITFFLGVLGNGLVIWVAGFRMPHTVTTIWYLNLALADFSFTATLPFLLVEMAMKEKWPFGWFLCKLVHIAVDVNLFGSVFLIAVIALDRCICVLHPVWAQNHRTVSLARNVVVGSWIFALILTLPLFLFLTTVRDARGDVHCRLSFVSWGNSVEERLNTAITFVTTRGIIRFIVSFSLPMSFVAICYGLITTKIHKKAFVNSSRPFRVLTGVVASFFICWFPFQLVALLGTVWLKEMQFSGSYKIIGRLVNPTSSLAFFNSCLNPILYVFMGQDFQERLIHSLSSRLQRALSEDSGHISDTRTNLASLPEDIEIKAI
  
Inhibitor
Name:
BDBM50097559
Synonyms:
CHEMBL3590073
Type:
Small organic molecule
Emp. Form.:
C31H35N5O3
Mol. Mass.:
525.6413
SMILES:
COc1ccc(NC(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NCC2(CCCCC2)c2ccccn2)cc1 |r|
Structure:
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