Target
Melatonin receptor type 1A
Ligand
BDBM50096967
Substrate
n/a
Meas. Tech.
ChEMBL_1499384 (CHEMBL3583713)
Ki
709±n/a nM
Citation
 de la Fuente Revenga, MFernández-Sáez, NHerrera-Arozamena, CMorales-García, JAAlonso-Gil, SPérez-Castillo, ACaignard, DHRivara, SRodríguez-Franco, MI Novel N-Acetyl Bioisosteres of Melatonin: Melatonergic Receptor Pharmacology, Physicochemical Studies, and Phenotypic Assessment of Their Neurogenic Potential. J Med Chem 58:4998-5014 (2015) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50096967
Synonyms:
CHEMBL3580916
Type:
Small organic molecule
Emp. Form.:
C14H15N3O2
Mol. Mass.:
257.2878
SMILES:
COc1ccc2[nH]cc(CCc3nnc(C)o3)c2c1
Structure:
Search PDB for entries with ligand similarity: