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Target
P2Y purinoceptor 14
Ligand
BDBM50304032
Substrate
n/a
Meas. Tech.
ChEMBL_1502487 (CHEMBL3592309)
EC50
2500000±n/a nM
Citation
 Trujillo, K; Paoletta, S; Kiselev, E; Jacobson, KA Molecular modeling of the human P2Y14 receptor: A template for structure-based design of selective agonist ligands. Bioorg Med Chem 23:4056-64 (2015) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 14
Synonyms:
P2Y14_HUMAN | P2RY14 | GPR105 | KIAA0001 | Purinergic receptor P2Y14 | Insulin Receptor-Related Protein (INSRR)
Type:
PROTEIN
Mol. Mass.:
38991.62
Organism:
Human
Description:
ChEMBL_1502487
Residue:
338
Sequence:
MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
  
Inhibitor
Name:
BDBM50304032
Synonyms:
URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE | Diphosphoric Acid 1''-alpha-D-[1''](2''-Fluoro-2''-Deoxy)Glucopyranosyl Ester 2-(uridin-5'-yl)ester | CHEMBL593830
Type:
Small organic molecule
Emp. Form.:
C15 H23 F N2 O16 P2
Mol. Mass.:
568.29284
SMILES:
OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](F)[C@@H](O)[C@@H]1O |r|
Structure:
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