Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 9
Ligand
BDBM50113447
Substrate
n/a
Meas. Tech.
ChEMBL_1510356
IC50
89±n/a nM
Citation
 Zhang, J; Romero, J; Chan, A; Goss, J; Stucka, S; Cross, J; Chamberlain, B; Varoglu, M; Chandonnet, H; Ryan, D; Lippa, B Biarylsulfonamide CCR9 inhibitors for inflammatory bowel disease. Bioorg Med Chem Lett 25:3661-4 (2015) [PubMed]  Article  BDB Entry
Target
Name:
C-C chemokine receptor type 9
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
42023.90
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1510356
Residue:
369
Sequence:
MTPTDFTSPIPNMADDYGSESTSSMEDYVNFNFTDFYCEKNNVRQFASHFLPPLYWLVFIVGALGNSLVILVYWYCTRVKTMTDMFLLNLAIADLLFLVTLPFWAIAAADQWKFQTFMCKVVNSMYKMNFYSCVLLIMCISVDRYIAIAQAMRAHTWREKRLLYSKMVCFTIWVLAAALCIPEILYSQIKEESGIAICTMVYPSDESTKLKSAVLTLKVILGFFLPFVVMACCYTIIIHTLIQAKKSSKHKALKVTITVLTVFVLSQFPYNCILLVQTIDAYAMFISNCAVSTNIDICFQVTQTIAFFHSCLNPVLYVFVGERFRRDLVKTLKNLGCISQAQWVSFTRREGSLKLSSMLLETTSGALSL
  
Inhibitor
Name:
BDBM50113447
Synonyms:
CHEMBL3604478
Type:
Small organic molecule
Emp. Form.:
C22H23ClN2O3S
Mol. Mass.:
430.948
SMILES:
CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(Cl)cc1-c1ncccc1CO
Structure:
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