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Target
P2Y purinoceptor 1
Ligand
BDBM50131061
Substrate
n/a
Meas. Tech.
ChEBML_1526464
EC50
37±n/a nM
Citation
 Azran, S; Danino, O; Förster, D; Kenigsberg, S; Reiser, G; Dixit, M; Singh, V; Major, DT; Fischer, B Identification of Highly Promising Antioxidants/Neuroprotectants Based on Nucleoside 5'-Phosphorothioate Scaffold. Synthesis, Activity, and Mechanisms of Action. J Med Chem 58:8427-43 (2015) [PubMed]  Article  BDB Entry
Target
Name:
P2Y purinoceptor 1
Synonyms:
ATP receptor | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1
Type:
Enzyme
Mol. Mass.:
42090.25
Organism:
Homo sapiens (Human)
Description:
P47900
Residue:
373
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILPEFKQNGDTSL
  
Inhibitor
Name:
BDBM50131061
Synonyms:
CHEMBL3634185
Type:
Small organic molecule
Emp. Form.:
C11H17N5O9P2S2
Mol. Mass.:
489.358
SMILES:
CSc1nc(N)c2ncn([C@@H]3O[C@H](COP(O)(=O)OP(O)(S)=O)[C@@H](O)[C@H]3O)c2n1 |r|
Structure:
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