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Target
P2Y purinoceptor 11
Ligand
BDBM50131061
Substrate
n/a
Meas. Tech.
ChEBML_1526465
EC50
900±n/a nM
Citation
 Azran, S; Danino, O; Förster, D; Kenigsberg, S; Reiser, G; Dixit, M; Singh, V; Major, DT; Fischer, B Identification of Highly Promising Antioxidants/Neuroprotectants Based on Nucleoside 5'-Phosphorothioate Scaffold. Synthesis, Activity, and Mechanisms of Action. J Med Chem 58:8427-43 (2015) [PubMed]  Article  BDB Entry
Target
Name:
P2Y purinoceptor 11
Synonyms:
P2Y purinoceptor 11 | P2Y11 | Purinergic receptor P2Y11
Type:
PROTEIN
Mol. Mass.:
40366.02
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1362532
Residue:
374
Sequence:
MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRKQRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSVIFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNCSVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSPGMTVAEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAALELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATAAPKPSEPQSRELSQ
  
Inhibitor
Name:
BDBM50131061
Synonyms:
CHEMBL3634185
Type:
Small organic molecule
Emp. Form.:
C11H17N5O9P2S2
Mol. Mass.:
489.358
SMILES:
CSc1nc(N)c2ncn([C@@H]3O[C@H](COP(O)(=O)OP(O)(S)=O)[C@@H](O)[C@H]3O)c2n1 |r|
Structure:
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