Reaction Details Report a problem with these data
Target
Carbonic anhydrase
Ligand
BDBM50028010
Substrate
n/a
Meas. Tech.
ChEMBL_1543853 (CHEMBL3749743)
Ki
140±n/a nM
Citation
 Vullo, D; Bhatt, A; Mahon, BP; McKenna, R; Supuran, CT Sulfonamide inhibition studies of thea-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA. Bioorg Med Chem Lett 26:401-5 (2016) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
4.2.1.1 | Carbonate dehydratase
Type:
PROTEIN
Mol. Mass.:
28438.71
Organism:
Sulfurihydrogenibium sp. (strain YO3AOP1)
Description:
ChEMBL_116696
Residue:
246
Sequence:
MRKILISAVLVLSSISISFAEHEWSYEGEKGPEHWAQLKPEFFWCKLKNQSPINIDKKYKVKANLPKLNLYYKTAKESEVVNNGHTIQINIKEDNTLNYLGEKYQLKQFHFHTPSEHTIEKKSYPLEIHFVHKTEDGKILVVGVMAKLGKTNKELDKILNVAPAEEGEKILDKNLNLNNLIPKDKRYMTYSGSLTTPPCTEGVRWIVLKKPISISKQQLEKLKSVMVNPNNRPVQEINSRWIIEGF
  
Inhibitor
Name:
BDBM50028010
Synonyms:
AD-810 | CHEBI:10127 | CI-912 | PD-110843 | Zonegran | Zonisamide
Type:
Small organic molecule
Emp. Form.:
C8H8N2O3S
Mol. Mass.:
212.226
SMILES:
OS(=N)(=O)Cc1noc2ccccc12
Structure:
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