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Target
Testis-specific serine/threonine-protein kinase 6
Ligand
BDBM50135286
Substrate
n/a
Meas. Tech.
ChEMBL_1543445 (CHEMBL3750164)
IC50
>10000±n/a nM
Citation
 Reddy, MV; Akula, B; Jatiani, S; Vasquez-Del Carpio, R; Billa, VK; Mallireddigari, MR; Cosenza, SC; Venkata Subbaiah, DR; Bharathi, EV; Pallela, VR; Ramkumar, P; Jain, R; Aggarwal, AK; Reddy, EP Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2). Bioorg Med Chem 24:521-44 (2016) [PubMed]  Article 
Target
Name:
Testis-specific serine/threonine-protein kinase 6
Synonyms:
CT72 | Cancer/testis antigen 72 | Serine/threonine-protein kinase SSTK | Small serine/threonine kinase | TSK-6 | TSSK-6 | Testis-specific kinase 6 | Testis-specific serine/threonine-protein kinase 6 | TSSK6_HUMAN | TSSK6 | SSTK
Type:
PROTEIN
Mol. Mass.:
30343.80
Organism:
Human
Description:
ChEMBL_109904
Residue:
273
Sequence:
MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAATDLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG
  
Inhibitor
Name:
BDBM50135286
Synonyms:
CHEMBL3745885
Type:
Small organic molecule
Emp. Form.:
C22H15F2N5O3S
Mol. Mass.:
467.09
SMILES:
Cn1c2nc(Nc3ccc4[nH]ccc4c3)ncc2cc(c1=O)S(=O)(=O)c1ccc(F)cc1F
Structure:
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