Target
CviR transcriptional regulator
Ligand
BDBM50136219
Substrate
n/a
Meas. Tech.
ChEMBL_1547614 (CHEMBL3755484)
IC50
90900±n/a nM
Citation
 Bucio-Cano, AReyes-Arellano, ACorrea-Basurto, JBello, MTorres-Jaramillo, JSalgado-Zamora, HCuriel-Quesada, EPeralta-Cruz, JAvila-Sorrosa, A Targeting quorum sensing by designing azoline derivatives to inhibit the N-hexanoyl homoserine lactone-receptor CviR: Synthesis as well as biological and theoretical evaluations. Bioorg Med Chem 23:7565-77 (2015) [PubMed]  Article 
Target
Name:
CviR transcriptional regulator
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
29723.76
Organism:
Chromobacterium violaceum
Description:
ChEMBL_765227
Residue:
265
Sequence:
MVISKPINARPLPAGLTASQQWTLLEWIHMAGHIETENELKAFLDQVLSQAPSERLLLALGRLNNQNQIQRLERVLNVSYPSDWLDQYMKENYAQHDPILRIHLGQGPVMWEERFNRAKGAEEKRFIAEATQNGMGSGITFSAASERNNIGSILSIAGREPGRNAALVAMLNCLTPHLHQAAIRVANLPPASPSNMPLSQREYDIFHWMSRGKTNWEIATILDISERTVKFHVANVIRKLNANNRTHAIVLGMHLAMPPSTVANE
  
Inhibitor
Name:
BDBM50136219
Synonyms:
CHEMBL3753564
Type:
Small organic molecule
Emp. Form.:
C15H22N2O
Mol. Mass.:
246.348
SMILES:
CCCCCCOc1ccc(cc1)C1=NCCN1 |t:14|
Structure:
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