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Target
Carbonic anhydrase 7
Ligand
BDBM50329822
Substrate
n/a
Meas. Tech.
ChEMBL_1572868 (CHEMBL3801004)
KON
200000 M-1s-1
Citation
 Talibov, VO; Linkuviene, V; Matulis, D; Danielson, UH Kinetically Selective Inhibitors of Human Carbonic Anhydrase Isozymes I, II, VII, IX, XII, and XIII. J Med Chem 59:2083-93 (2016) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | Carbonate dehydratase VII | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) | CAH7_HUMAN | CA7 | Carbonic anhydrase
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Human
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50329822
Synonyms:
5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chlorobenzenesulfonamide | CHEMBL1272242 | N-alkylated benzimidazole derivative, 4d | carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 5
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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