Reaction Details Report a problem with these data
Target
Aminopeptidase B
Ligand
BDBM50010157
Substrate
n/a
Meas. Tech.
ChEMBL_1580949 (CHEMBL3812617)
IC50
3500±n/a nM
Citation
 Gunaydin, H; Bartberger, MD Stacking with No Planarity? ACS Med Chem Lett 7:341-4 (2016) [PubMed]  Article 
Target
Name:
Aminopeptidase B
Synonyms:
AMPB_HUMAN | APB | Aminopeptidase | Ap-B | Arginine aminopeptidase | Arginyl aminopeptidase | RNPEP
Type:
PROTEIN
Mol. Mass.:
72586.33
Organism:
Homo sapiens (Human)
Description:
ChEMBL_36048
Residue:
650
Sequence:
MASGEHSPGSGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVLLTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGPNKFFFQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAISPWKTYQLVYFLDKILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGKQKYTLPLYHAMMGGSEVAQTLAKETFASTASQLHSNVVNYVQQIVAPKGS
  
Inhibitor
Name:
BDBM50010157
Synonyms:
CHEMBL3251698
Type:
Small organic molecule
Emp. Form.:
C16H30N2O4
Mol. Mass.:
314.4204
SMILES:
CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)CC1CCCCC1)C(O)=O |r|
Structure:
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