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Target
D(4) dopamine receptor
Ligand
BDBM50182746
Substrate
n/a
Meas. Tech.
ChEMBL_1586515 (CHEMBL3821454)
Ki
145±n/a nM
Citation
 Ofori, E; Zhu, XY; Etukala, JR; Peprah, K; Jordan, KR; Adkins, AA; Bricker, BA; Kang, HJ; Huang, XP; Roth, BL; Ablordeppey, SY Design and synthesis of dual 5-HT1A and 5-HT7 receptor ligands. Bioorg Med Chem 24:3464-71 (2016) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(4) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.4 | DRD4_RAT | Dopamine receptor | Drd4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41307.65
Organism:
RAT
Description:
DOPAMINE D4.4 0 RAT::P30729
Residue:
387
Sequence:
MGNSSATGDGGLLAGRGPESLGTGTGLGGAGAAALVGGVLLIGMVLAGNSLVCVSVASERILQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASIFNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVAAPVVCGLNDVPGRDPTVCCLEDRDYVVYSSICSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPVSDPTQGPLFSDCPPPSPSLRTSPTVSSRPESDLSQSPCSPGCLLPDAALAQPPAPSSRRKRGAKITGRERKAMRVLPVVVGAFLMCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVNSALNPIIYTIFNAEFRSVFRKTLRLRC
  
Inhibitor
Name:
BDBM50182746
Synonyms:
CHEMBL3819556
Type:
Small organic molecule
Emp. Form.:
C18H21ClFNS
Mol. Mass.:
337.882
SMILES:
Cl.Fc1ccc(SCCCN2CCc3ccccc3C2)cc1
Structure:
Search PDB for entries with ligand similarity: