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Target
Adenosine receptor A2b
Ligand
BDBM50187588
Substrate
n/a
Meas. Tech.
ChEMBL_1590505 (CHEMBL3831087)
Ki
>1000±n/a nM
Citation
 Szymanska, E; Drabczynska, A; Karcz, T; Müller, CE; Köse, M; Karolak-Wojciechowska, J; Fruzinski, A; Schabikowski, J; Doroz-Plonka, A; Handzlik, J; Kiec-Kononowicz, K Similarities and differences in affinity and binding modes of tricyclic pyrimido- and pyrazinoxanthines at human and rat adenosine receptors. Bioorg Med Chem 24:4347-4362 (2016) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_RAT | Adenosine receptor | Adora2b
Type:
PROTEIN
Mol. Mass.:
36378.84
Organism:
Rattus norvegicus
Description:
ChEMBL_32934
Residue:
332
Sequence:
MQLETQDALYVALELVIAALAVAGNVLVCAAVGASSALQTPTNYFLVSLATADVAVGLFAIPFAITISLGFCTDFHSCLFLACFVLVLTQSSIFSLLAVAVDRYLAIRVPLRYKGLVTGTRARGIIAVLWVLAFGIGLTPFLGWNSKDRATSNCTEPGDGITNKSCCPVKCLFENVVPMSYMVYFNFFGCVLPPLLIMMVIYIKIFMVACKQLQHMELMEHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAINCITLFHPALAKDKPKWVMNVAILLSHANSVVNPIVYAYRNRDFRYSFHRIISRYVLCQTDTKGGSGQAGGQSTFSLSL
  
Inhibitor
Name:
BDBM50187588
Synonyms:
CHEMBL3827201
Type:
Small organic molecule
Emp. Form.:
C29H42N6O3
Mol. Mass.:
522.6822
SMILES:
CCCCn1c2nc3N(CCCn3c2c(=O)n(CCCC)c1=O)c1ccc(OCCN2CCCCC2)cc1
Structure:
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