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Target
CDGSH iron-sulfur domain-containing protein 1
Ligand
BDBM50012957
Substrate
n/a
Meas. Tech.
ChEMBL_1620948 (CHEMBL3863231)
Ki
1671±n/a nM
Citation
 Geldenhuys, WJ; Yonutas, HM; Morris, DL; Sullivan, PG; Darvesh, AS; Leeper, TC Identification of small molecules that bind to the mitochondrial protein mitoNEET. Bioorg Med Chem Lett 26:5350-5353 (2016) [PubMed]  Article 
Target
Name:
CDGSH iron-sulfur domain-containing protein 1
Synonyms:
C10orf70 | CISD1 | CISD1_HUMAN | MitoNEET | ZCD1
Type:
PROTEIN
Mol. Mass.:
12206.48
Organism:
Homo sapiens (Human)
Description:
ChEMBL_766432
Residue:
108
Sequence:
MSLTSSSSVRVEWIAAVTIAAGTAAIGYLAYKRFYVKDHRNKAMINLHIQKDNPKIVHAFDMEDLGDKAVYCRCWRSKKFPFCDGAHTKHNEETGDNVGPLIIKKKET
  
Inhibitor
Name:
BDBM50012957
Synonyms:
1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea | 1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea | 5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide | 5-chloro-N-(2-{4-[N-(N-cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide | CHEMBL472 | GLYBURIDE | Glibenclamide | US20230348371, Compound 5
Type:
Small organic molecule
Emp. Form.:
C23H28ClN3O5S
Mol. Mass.:
494.004
SMILES:
COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1
Structure:
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