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Target
Beta-1 adrenergic receptor
Ligand
BDBM25753
Substrate
n/a
Meas. Tech.
ChEMBL_1633549 (CHEMBL3876341)
IC50
210±n/a nM
Citation
 Gunia-Krzyzak, A; Zelaszczyk, D; Rapacz, A; Zeslawska, E; Waszkielewicz, AM; Panczyk, K; Sloczynska, K; Pekala, E; Nitek, W; Filipek, B; Marona, H Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH Bioorg Med Chem 25:471-482 (2017) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
adrenergic Beta1 | ADRB1_HUMAN | ADRB1 | ADRB1R | Beta-1 adrenoceptor | B1AR | Beta-1 adrenoreceptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
51338.40
Organism:
Human
Description:
P08588
Residue:
477
Sequence:
MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAGMGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVCTVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAPLANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQGLLCCARRAARRRHATHGDRPRASGCLARPGPPPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV
  
Inhibitor
Name:
BDBM25753
Synonyms:
Artrenolol | 2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide | Tenormin | CHEMBL24 | Tenormine | Atenolol
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: