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Target
cAMP-dependent protein kinase catalytic subunit gamma
Ligand
BDBM15203
Substrate
n/a
Meas. Tech.
ChEMBL_161403 (CHEMBL768312)
IC50
6000±n/a nM
Citation
 Ricouart, A; Gesquiere, JC; Tartar, A; Sergheraert, C Design of potent protein kinase inhibitors using the bisubstrate approach. J Med Chem 34:73-8 (1991) [PubMed]  Article 
Target
Name:
cAMP-dependent protein kinase catalytic subunit gamma
Synonyms:
PKA C-gamma | cAMP-dependent protein kinase catalytic subunit gamma | cAMP-dependent protein kinase (PKA) | KAPCG_HUMAN | PRKACG
Type:
PROTEIN
Mol. Mass.:
40442.03
Organism:
Human
Description:
ChEMBL_104720
Residue:
351
Sequence:
MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
  
Inhibitor
Name:
BDBM15203
Synonyms:
Isoquinoline-5-sulfonic acid piperazin-1 ylamide | 5-(piperazine-1-sulfonyl)isoquinoline | CHEMBL75773 | isoquinoline-5-sulfonamide 18
Type:
Small organic molecule
Emp. Form.:
C13H15N3O2S
Mol. Mass.:
277.09
SMILES:
O=S(=O)(N1CCNCC1)c1cccc2cnccc12
Structure:
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