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Target
5-hydroxytryptamine receptor 1D
Ligand
BDBM50056445
Substrate
n/a
Meas. Tech.
ChEMBL_1966 (CHEMBL617571)
Kd
10.0±n/a nM
Citation
 King, FD; Brown, AM; Gaster, LM; Kaumann, AJ; Medhurst, AD; Parker, SG; Parsons, AA; Patch, TL; Raval, P (+/-) 3-Amino-6-carboxamido-1,2,3,4-tetrahydrocarbazole: a conformationally restricted analogue of 5-carboxamidotryptamine with selectivity for the serotonin 5-HT1D receptor. J Med Chem 36:1918-9 (1993) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1D
Synonyms:
5HT1D_PIG | HTR1D | Serotonin 1d (5-HT1d) receptor
Type:
PROTEIN
Mol. Mass.:
32680.56
Organism:
Sus scrofa
Description:
ChEMBL_1963
Residue:
291
Sequence:
AMTDLLVSILVMPISIPYTITQTWSFGQLLCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAIVWAISICISIPPLFWRQARAHEEISDCLVNTSQISYTIYSTCGAFYIPSLLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNPSLHEGHSHSAGSPLFFNHVKIKLADSVLERKRISAARERKATKTLGIILGAFIICWLPFFVASLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKVV
  
Inhibitor
Name:
BDBM50056445
Synonyms:
1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroergolin-8-yl]urea | CHEMBL157138 | N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylurea | lisuride | lisuride, (S)
Type:
Small organic molecule
Emp. Form.:
C20H26N4O
Mol. Mass.:
338.4466
SMILES:
CCN(CC)C(=O)N[C@@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:23|
Structure:
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