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Target
Carbonic anhydrase 2
Ligand
BDBM50028010
Substrate
n/a
Meas. Tech.
ChEBML_1652371
Ki
35±n/a nM
Citation
 Del Prete, S; Vullo, D; Di Fonzo, P; Osman, SM; AlOthman, Z; Donald, WA; Supuran, CT; Capasso, C Sulfonamide inhibition profile of theż-carbonic anhydrase identified in the genome of the pathogenic bacterium Burkholderia pseudomallei the etiological agent responsible of melioidosis. Bioorg Med Chem Lett 27:490-495 (2017) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50028010
Synonyms:
AD-810 | CHEBI:10127 | CI-912 | PD-110843 | Zonegran | Zonisamide
Type:
Small organic molecule
Emp. Form.:
C8H8N2O3S
Mol. Mass.:
212.226
SMILES:
OS(=N)(=O)Cc1noc2ccccc12
Structure:
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