Reaction Details Report a problem with these data
Target
Vitamin K epoxide reductase complex subunit 1
Ligand
BDBM768
Substrate
n/a
Meas. Tech.
ChEMBL_1657647 (CHEMBL4007117)
Ki
200±n/a nM
Citation
Montagut-Romans, A; Boulven, M; Jacolot, M; Moebs-Sanchez, S; Hascoët, C; Hammed, A; Besse, S; Lemaire, M; Benoit, E; Lattard, V; Popowycz, F Synthesis and biological evaluation of C-3 aliphatic coumarins as vitamin K antagonists. Bioorg Med Chem Lett 27:1598-1601 (2017) [PubMed] Article
More Info.:
Target
Name:
Vitamin K epoxide reductase complex subunit 1
Synonyms:
VKOR1_RAT | Vitamin K epoxide reductase complex subunit 1 (rVKORC1) | Vkorc1
Type:
Enzyme
Mol. Mass.:
17793.51
Organism:
Rattus norvegicus (Rat)
Description:
Q6TEK4
Residue:
161
Sequence:
MGTTWRSPGRLRLALCLAGLALSLYALHVKAARARNEDYRALCDVGTAISCSRVFSSRWGRGFGLVEHVLGADSILNQSNSIFGCMFYTIQLLLGCLRGRWASILLILSSLVSVAGSLYLAWILFFVLYDFCIVCITTYAINAGLMLLSFQKVPEHKVKKP