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Target
D(3) dopamine receptor
Ligand
BDBM22869
Substrate
n/a
Ki
880±n/a nM
Comments
PDSP_552
Citation
 Schoemaker, H; Claustre, Y; Fage, D; Rouquier, L; Chergui, K; Curet, O; Oblin, A; Gonon, F; Carter, C; Benavides, J; Scatton, B Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity. J Pharmacol Exp Ther 280:83-97 (1997) [PubMed] 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40792.06
Organism:
Bovine
Description:
F1N454
Residue:
367
Sequence:
MAPLNQLGGHINATCAAENSTGAGRARPHAYYALSYCALILAIVFGNVLVCVAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRVCCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQQGTGQSSCRRVALMITAVWLLSFAVSCPLLFGFNTTGDPSICSISNPDFVLYSSVVSFYLPFGVTVLVYARIYVVLRQRRRKRILTRQNSQCLSVRPSFPQQPLSPGQTHMELKRYYSICQDTALGTPGFQEGEGDLKREGRTRNSLMPLREKKATQMLVIVLGTFIVCWLPFFLTHVLNTHCRACHVSPQLYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM22869
Synonyms:
6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene | Leponex | CLOZARIL | Clozapine | US10259786, Clozapine
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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