Reaction Details
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Report a problem with these dataTarget
Melatonin receptor
Ligand
BDBM50240440
Substrate
n/a
Ki
0.3±n/a nM
Comments
PDSP_122
Citation
Dubocovich, ML; Masana, MI; Iacob, S; Sauri, DM Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor. Naunyn Schmiedebergs Arch Pharmacol 355:365-75 (1997) [PubMed] Article More Info.:
Target
Name:
Melatonin receptor
Synonyms:
Melatonin receptor | Melatonin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
13287.02
Organism:
Rabbit
Description:
Q9BE38
Residue:
114
Sequence:
MIWMLTLVAVMPNLHTGTLQYDPRVYSCTFSQSVSSAYTIAVVVFHFIIPMLMSSCCYLRIWILVLQVRRRVKPDNKPKLKPQDFRNFITMFVVFVLFAICWAPLNFIVLLGRS
Inhibitor
Name:
BDBM50240440
Synonyms:
CHEMBL285718 | 4-P-PDOT | N-(4-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propionamide | N-(4-phenyl-1,2,3,4-tetrahydronaphthalen-2-yl)propionamide
Type:
Small organic molecule
Emp. Form.:
C19H21NO
Mol. Mass.:
279.16
SMILES:
CCC(=O)NC1CC(c2ccccc2)c2ccccc2C1
Structure:
