Reaction Details Report a problem with these data
Target
Galanin receptor type 2
Ligand
BDBM85070
Substrate
n/a
Ki
0.46±n/a nM
Comments
PDSP_865
Citation
 Howard, AD; Tan, C; Shiao, LL; Palyha, OC; McKee, KK; Weinberg, DH; Feighner, SD; Cascieri, MA; Smith, RG; Van Der Ploeg, LH; Sullivan, KA Molecular cloning and characterization of a new receptor for galanin. FEBS Lett 405:285-90 (1997) [PubMed]  Article 
Target
Name:
Galanin receptor type 2
Synonyms:
Galanin R2 | Galanin receptor type 2 | GALR2_RAT | Galr2 | Galnr2 | Galanin receptor 2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40697.04
Organism:
Rat
Description:
Galanin R2 GALR2 RAT::O08726
Residue:
372
Sequence:
MNGSGSQGAENTSQEGGSGGWQPEAVLVPLFFALIFLVGTVGNALVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDLCTFVFSYLLPVLVLSLTYARTLRYLWRTVDPVTAGSGSQRAKRKVTRMIIIVAVLFCLCWMPHHALILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRKICAGLLRPAPRRASGRVSILAPGNHSGSMLEQESTDLTQVSEAAGPLVPPPALPNCTASSRTLDPAC
  
Inhibitor
Name:
BDBM85070
Synonyms:
Galanin, Porcine
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CCC(C)C(NC(=O)C(C)NC(=O)C(Cc1cnc[nH]1)NC(=O)C1CCCN1C(=O)CNC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(O)cc1)NC(=O)CNC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CN)C(C)O)C(=O)NC(CC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(CCCN=C(N)N)C(=O)NC(CO)C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1cnc[nH]1)C(=O)NC(CC(O)=O)C(=O)NC(CCCCN)C(=O)NC(Cc1ccc(O)cc1)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(C)C(N)=O
Structure:
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