Reaction Details Report a problem with these data
Target
Gamma-aminobutyric acid type B receptor subunit 1
Ligand
BDBM24184
Substrate
n/a
Ki
5±n/a nM
Comments
PDSP_3487
Citation
 Chebib, M; Vandenberg, RJ; Froestl, W; Johnston, GA Unsaturated phosphinic analogues of gamma-aminobutyric acid as GABA(C) receptor antagonists. Eur J Pharmacol 329:223-9 (1997) [PubMed] 
Target
Name:
Gamma-aminobutyric acid type B receptor subunit 1
Synonyms:
GABA B | Gamma-aminobutyric acid type B receptor subunit 1 (GABA) | GABR1_RAT | Gabbr1 | Gamma-aminobutyric acid (GABA) B receptor 1 | Gb1 | GABA-B-R1 | GABA-B receptor 1 | GABA uptake | GABA-BR1 | GABA B receptor | GABABR1
Type:
Protein
Mol. Mass.:
108221.06
Organism:
Rat
Description:
Q9Z0U4
Residue:
960
Sequence:
MLLLLLVPLFLRPLGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLPALDGARVEFRCDPDFHLVGSSRSVCSQGQWSTPKPHCQVNRTPHSERRAVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDARIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKTYDPSINCTVEEMTEAVEGHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRSQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSKKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSETQDTMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKEERVSELRHQLQSRQQLRSRRHPPTPPDPSGGLPRGPSEPPDRLSCDGSRVHLLYK
  
Inhibitor
Name:
BDBM24184
Synonyms:
(3-aminopropyl)phosphinic acid | CHEMBL112203 | CGP27492 | 3-aminopropylphosphinic derivative, 1
Type:
Small organic molecule
Emp. Form.:
C3H10NO2P
Mol. Mass.:
123.04
SMILES:
NCCCP(O)=O
Structure:
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