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Target
Gamma-aminobutyric acid receptor subunit alpha-3
Ligand
BDBM24184
Substrate
n/a
Ki
2470±n/a nM
Comments
PDSP_3487
Citation
 Chebib, M; Vandenberg, RJ; Froestl, W; Johnston, GA Unsaturated phosphinic analogues of gamma-aminobutyric acid as GABA(C) receptor antagonists. Eur J Pharmacol 329:223-9 (1997) [PubMed] 
Target
Name:
Gamma-aminobutyric acid receptor subunit alpha-3
Synonyms:
GABA receptor alpha-3 subunit | GABA A Alpha3Beta3Gamma2 | GABA C | Gamma-aminobutyric acid receptor subunit alpha-3 | GABA-A receptor | agonist GABA site | GBRA3_HUMAN | GABRA3 | GABA A receptor alpha-3/beta-2/gamma-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55175.47
Organism:
Human
Description:
GABA A Alpha3Beta1Gamma2 0 HUMAN::P34903
Residue:
492
Sequence:
MIITQTSHCYMTSLGILFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDSTDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSASSTPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVNRESAIKGMIRKQ
  
Inhibitor
Name:
BDBM24184
Synonyms:
(3-aminopropyl)phosphinic acid | CHEMBL112203 | CGP27492 | 3-aminopropylphosphinic derivative, 1
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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