Reaction Details Report a problem with these data
Target
Prostacyclin receptor
Ligand
BDBM85179
Substrate
n/a
Ki
10±n/a nM
Comments
PDSP_518
Citation
 Kiriyama, M; Ushikubi, F; Kobayashi, T; Hirata, M; Sugimoto, Y; Narumiya, S Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br J Pharmacol 122:217-24 (1997) [PubMed]  Article 
Target
Name:
Prostacyclin receptor
Synonyms:
PI2R_MOUSE | Prostacyclin receptor | Prostaglandin I | Prostaglandin I2 | Ptgir
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44475.65
Organism:
MOUSE
Description:
Prostaglandin I2 PTGIR MOUSE::P43252
Residue:
415
Sequence:
MMASDGHPGPPSVTPGSPLSAGGREWQGMAGSCWNITYVQDSVGPATSTLMFVAGVVGNGLALGILGARRRSHPSAFAVLVTGLAVTDLLGTCFLSPAVFVAYARNSSLLGLAHGGTMLCDTFAFAMTFFGLASTLILFAMAVERCLALSHPYLYAQLDGPRCARFALPSIYAFCCLFCSLPLLGLGEHQQYCPGSWCFIRMRSAQPGGCAFSLAYASLMALLVTSIFFCNGSVTLSLYHMYRQQRRHHGSFVPTSRAREDEVYHLILLALMTVIMAVCSLPLMIRGFTQAIAPDSREMGDLLAFRFNAFNPILDPWVFILFRKAVFQRLKFWLCCLCARSVHGDLQAPLSRPASGRRDPPAPTSLQAKEGSWVPLSSWGTGQVAPLTAVPLTGGDGCSVGMPSKSEAIAACSLC
  
Inhibitor
Name:
BDBM85179
Synonyms:
CAS_94079-80-8 | CICAPROST | NSC_72023
Type:
Small organic molecule
Emp. Form.:
C22H30O5
Mol. Mass.:
374.4706
SMILES:
CCC#CCC(C)C(O)C#CC1C(O)CC2CC(CC12)=CCOCC(O)=O |w:20.22|
Structure:
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