Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 4
Ligand
BDBM29525
Substrate
n/a
Ki
0.03±n/a nM
Comments
PDSP_880
Citation
 Claeysen, S; Faye, P; Sebben, M; Lemaire, S; Bockaert, J; Dumuis, A Cloning and expression of human 5-HT4S receptors. Effect of receptor density on their coupling to adenylyl cyclase. Neuroreport 8:3189-96 (1997) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 4
Synonyms:
5-HT-4 | 5-HT4 | 5-HT4L | 5-HT4S | 5-hydroxytryptamine receptor 4 | 5HT4R_RAT | Htr4 | Serotonin (5-HT) receptor | Serotonin 4 (5-HT4) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46117.31
Organism:
RAT
Description:
5-HT4 HTR4 RAT::Q62758
Residue:
406
Sequence:
MDRLDANVSSNEGFGSVEKVVLLTFFAMVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVNAFGAIELVQDIWFYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDVIEKRKFNHNSNSTFCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQTADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEKVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPVIRRPQDNDLEDSCSLKRSQS
  
Inhibitor
Name:
BDBM29525
Synonyms:
3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 113808 | [3H]GR113808
Type:
radiolabeled ligand
Emp. Form.:
C19H27N3O4S
Mol. Mass.:
393.5
SMILES:
Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12
Structure:
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