Reaction Details Report a problem with these data
Target
Galanin receptor type 3
Ligand
BDBM85205
Substrate
n/a
Ki
49.6±n/a nM
Comments
PDSP_856
Citation
 Wang, S; He, C; Hashemi, T; Bayne, M Cloning and expressional characterization of a novel galanin receptor. Identification of different pharmacophores within galanin for the three galanin receptor subtypes. J Biol Chem 272:31949-52 (1997) [PubMed]  Article 
Target
Name:
Galanin receptor type 3
Synonyms:
GALR3_RAT | Galanin R3 | Galanin receptor type 3 | Galnr3 | Galr3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40439.51
Organism:
RAT
Description:
Galanin R3 GALR3 RAT::O88626
Residue:
370
Sequence:
MADIQNISLDSPGSVGAVAVPVIFALIFLLGMVGNGLVLAVLLQPGPSAWQEPRSTTDLFILNLAVADLCFILCCVPFQAAIYTLDAWLFGAFVCKTVHLLIYLTMYASSFTLAAVSLDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLCFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYSLASRHFRARFRRLWPCGRRRHRHHHRAHRALRRVQPASSGPAGYPGDARPRGWSMEPRGDALRGGGETRLTLSPRGPQ
  
Inhibitor
Name:
BDBM85205
Synonyms:
Galanin (1-16) | Galanin (1-16), rat
Type:
Small organic molecule
Emp. Form.:
C78H117N21O20
Mol. Mass.:
1668.8923
SMILES:
CCC(C)C(NC(=O)C(C)NC(=O)C(Cc1cnc[nH]1)NC(=O)C1CCCN1C(=O)CNC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccc(O)cc1)NC(=O)CNC(=O)C(C)NC(=O)C(CO)NC(=O)C(CC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CN)C(C)O)C(N)=O
Structure:
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