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Target
Aromatase [1-48]
Ligand
BDBM85251
Substrate
n/a
Meas. Tech.
Biological Assay
IC50
133±n/a nM
Citation
 Pouget, C; Yahiaoui, S; Fagnere, C; Habrioux, G; Chulia, AJ Synthesis and biological evaluation of 4-imidazolylflavans as nonsteroidal aromatase inhibitors. Bioorg Chem 32:494-503 (2004) [PubMed]  Article 
Target
Name:
Aromatase [1-48]
Synonyms:
ARO1 | Aromatase cytochrome P450 | CP19A_HUMAN | CYAR | CYP19 | CYP19A1
Type:
Protein
Mol. Mass.:
5299.77
Organism:
Homo sapiens (Human)
Description:
Q16449
Residue:
48
Sequence:
MVLEMLNPIHYNITSIVPEAMPAATMPVLLLTGLFLLVWNYEGTSSIP
  
Inhibitor
Name:
BDBM85251
Synonyms:
2,4-Trans-4'-cyano-4-imidazolyl-7-methoxyflavan, 3c
Type:
Small organic molecule
Emp. Form.:
C20H17N3O2
Mol. Mass.:
331.3679
SMILES:
COc1ccc2C(CC(Oc2c1)c1ccc(cc1)C#N)n1ccnc1
Structure:
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