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Target
Prostaglandin-H2 D-isomerase
Ligand
BDBM85347
Substrate
n/a
Ki
2600±n/a nM
Comments
PDSP_459
Citation
 Arimura, A; Yasui, K; Kishino, J; Asanuma, F; Hasegawa, H; Kakudo, S; Ohtani, M; Arita, H Prevention of allergic inflammation by a novel prostaglandin receptor antagonist, S-5751. J Pharmacol Exp Ther 298:411-9 (2001) [PubMed] 
Target
Name:
Prostaglandin-H2 D-isomerase
Synonyms:
PDS | PGD2 | PTGDS | PTGDS_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
21031.11
Organism:
Homo sapiens (Human)
Description:
PGD2 0 HUMAN::P41222
Residue:
190
Sequence:
MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKKAALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYRSPHWGSTYSVSVVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIVFLPQTDKCMTEQ
  
Inhibitor
Name:
BDBM85347
Synonyms:
BWA868C | CAS_122021 | NSC_122021
Type:
Small organic molecule
Emp. Form.:
C25H37N3O5
Mol. Mass.:
459.5784
SMILES:
OC(CNn1c(CCCCCCC(O)=O)c(O)n(Cc2ccccc2)c1=O)C1CCCCC1
Structure:
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