Ki Summary

Reaction Details

Report a problem with these data

Target

Thyrotropin-releasing hormone receptor

Ligand

BDBM86217

Substrate

n/a

3000±n/a nM

Comments

PDSP_3208

Citation

Lu, X; Bidaud, I; Ladram, A; Gershengorn, MC Pharmacological studies of thyrotropin-releasing hormone (TRH) receptors from Xenopus laevis: is xTRHR3 a TRH receptor? Endocrinology 144:1842-6 (2003) [PubMed] Article

More Info.:

Get all data from this article

Target

Name:

Thyrotropin-releasing hormone receptor

Synonyms:

thyrotropin-releasing hormone R1 | Thyrotropin-releasing hormone receptor 1 | TRHR

Type:

Enzyme Catalytic Domain

Mol. Mass.:

44987.02

Organism:

African clawed frog

Description:

Q9DDR1

Residue:

397

Sequence:

MDNVTFAELNATELQKREWHGLEYQVVTVFLVVVICGLGIVGNVMVVLVVLQTKHMRTPTNCYLVSLAIADLIVLVAAGLPNITESVYGSWVYGYIGCLCITYLQYLGINASSCSITAFTVERYLAICHPIKAQFLCTISRAKKIIVFVWAFTSLYCLMWFFLLDLNTTIYKDATVVNCGYRVPRSYYSPIYLIDFGIFYAVPMTLATVLYGLIARILFLNPIPSDPKENSKIRKNDATHQTKAFNSKMSSRCSNNTIASRRQVTKMLAVVVLLFAFLWMPYRTLVVVNSFLSRPYLQTWFVLFCRICIYLNSAINPVIYNLMSQKFRAAFQKLCKCKKKRSEKPTNYGLALNYSVIKESSNGGSPDHFSTELEDITVTDNYLSTSKMSFDDTCLPT

Inhibitor

Name:

BDBM86217

Synonyms:

Desaza1TRH

Type:

Small organic molecule

Emp. Form.:

n/a

Mol. Mass.:

n/a

SMILES:

NC(=O)C1CCCN1C(=O)C(Cc1cnc[nH]1)NC(=O)C1CCC(=O)C1

Structure: