Reaction Details Report a problem with these data
Target
Alpha-2C adrenergic receptor
Ligand
BDBM86276
Substrate
n/a
Ki
66.6±n/a nM
Comments
PDSP_4921
Citation
 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Receptor affinities of dopamine D1 receptor-selective novel phenylbenzazepines. Eur J Pharmacol 474:137-40 (2003) [PubMed]  Article 
Target
Name:
Alpha-2C adrenergic receptor
Synonyms:
adrenergic Alpha2C | Alpha-2C adrenergic receptor | ADA2C_RAT | Adra2c | Adrenergic receptor alpha | adrenergic Alpha2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49890.50
Organism:
Rat
Description:
adrenergic Alpha2 0 RAT::P22086
Residue:
458
Sequence:
MASPALAAALAAAAAEGPNGSDAGEWGSGGGANASGTDWGPPPGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSFYRRPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRGPAGPDGASPTTENGLGKAAGENGHCAPPRTEVEPDESSAAERRRRRGALRRGGRRREGAEGDTGSADGPGPGLAAEQGARTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
  
Inhibitor
Name:
BDBM86276
Synonyms:
NSC_0 | CAS_0 | MCL-207
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CN1CCc2c(Cl)c(O)c(O)cc2C(C1)c1ccccc1C
Structure:
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