Reaction Details Report a problem with these data
Target
Alpha-2C adrenergic receptor
Ligand
BDBM86273
Substrate
n/a
Ki
365±n/a nM
Comments
PDSP_4931
Citation
 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Receptor affinities of dopamine D1 receptor-selective novel phenylbenzazepines. Eur J Pharmacol 474:137-40 (2003) [PubMed]  Article 
Target
Name:
Alpha-2C adrenergic receptor
Synonyms:
adrenergic Alpha2C | Alpha-2C adrenergic receptor | ADA2C_RAT | Adra2c | Adrenergic receptor alpha | adrenergic Alpha2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49890.50
Organism:
Rat
Description:
adrenergic Alpha2 0 RAT::P22086
Residue:
458
Sequence:
MASPALAAALAAAAAEGPNGSDAGEWGSGGGANASGTDWGPPPGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSFYRRPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRGPAGPDGASPTTENGLGKAAGENGHCAPPRTEVEPDESSAAERRRRRGALRRGGRRREGAEGDTGSADGPGPGLAAEQGARTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
  
Inhibitor
Name:
BDBM86273
Synonyms:
MCL-211
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CN1CCc2c(cc(O)c(O)c2Br)[C@@H](C1)c1cccc(c1)C(F)(F)F |r|
Structure:
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