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Target
Neuronal acetylcholine receptor subunit alpha-4
Ligand
BDBM10759
Substrate
n/a
Ki
33±n/a nM
Comments
PDSP_229
Citation
 Jensen, AA; Mikkelsen, I; Frølund, B; Bräuner-Osborne, H; Falch, E; Krogsgaard-Larsen, P Carbamoylcholine homologs: novel and potent agonists at neuronal nicotinic acetylcholine receptors. Mol Pharmacol 64:865-75 (2003) [PubMed]  Article 
Target
Name:
Neuronal acetylcholine receptor subunit alpha-4
Synonyms:
Neuronal acetylcholine receptor subunit alpha 4 beta 2 | Cholinergic, Nicotinic Alpha4Beta2 | Neuronal acetylcholine receptor subunit alpha-4 | Cholinergic, Nicotinic Alpha4Beta4 | Neuronal acetylcholine receptor protein alpha-4 subunit | Neuronal acetylcholine receptor (alpha4beta2 nAChR) | Neuronal acetylcholine receptor | ACHA4_RAT | Chrna4 | Acra4
Type:
Enzyme
Mol. Mass.:
70196.44
Organism:
Rat
Description:
P09483
Residue:
630
Sequence:
MANSGTGAPPPLLLLPLLLLLGTGLLPASSHIETRAHAEERLLKRLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPGDYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHLFYDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLVSMHSRVDQLDFWESGEWVIVDAVGTYNTRKYECCAEIYPDITYAFIIRRLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKVTLCISVLLSLTVFLLLITEIIPSPTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHTMPAWVRRVFLDIVPRLLFMKRPSVVKDNCRRLIESMHKMANAPRFWPEPVGEPGILSDICNQGLSPAPTFCNPTDTAVETQPTCRSPPLEVPDLKTSEVEKASPCPSPGSCPPPKSSSGAPMLIKARSLSVQHVPSSQEAAEDGIRCRSRSIQYCVSQDGAASLADSKPTSSPTSLKARPSQLPVSDQASPCKCTCKEPSPVSPVTVLKAGGTKAPPQHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKEDWKYVAMVIDRIFLWMFIIVCLLGTVGLFLPPWLAAC
  
Inhibitor
Name:
BDBM10759
Synonyms:
2-acetoxyethyl(trimethyl)ammonium;perchlorate | 2-acetoxyethyl(trimethyl)ammonium;bromide | acetylcholine chloride | cid_6060 | CHEMBL667 | [2-(acetyloxy)ethyl]trimethylazanium | acetylcholine | US10667515, Compound ACh
Type:
Small Organic Molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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