Reaction Details Report a problem with these data
Target
Serum paraoxonase/arylesterase 1
Ligand
BDBM92331
Substrate
n/a
Meas. Tech.
Paraoxonase Activity Assay
pH
10.5000±0.0000
Temperature
298.1500±0.0000 K
Ki
9000±0.0 nM
IC50
136000±0.0 nM
Citation
 Ekinci, D; Beydemir, S Effect of some analgesics on paraoxonase-1 purified from human serum. J Enzyme Inhib Med Chem 24:1034-9 (2009) [PubMed]  Article 
Target
Name:
Serum paraoxonase/arylesterase 1
Synonyms:
K-45 | Paraoxonase (hPON1) | A-esterase 1 | Aromatic esterase 1 | Serum paraoxonase 1 (PON1) | Serum aryldialkylphosphatase 1 | Paraoxonase 1 (PON1) | PON 1 | Paraoxonase (PON1) | PON1_HUMAN | PON1 | PON
Type:
Enzyme
Mol. Mass.:
39719.73
Organism:
Human
Description:
P27169
Residue:
355
Sequence:
MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPNGLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTFTDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYGTNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAELLAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPPASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL
  
Inhibitor
Name:
BDBM92331
Synonyms:
Lornoxicam
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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