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Target
Prolyl 4-hydroxylase subunit alpha-1
Ligand
BDBM92715
Substrate
n/a
Meas. Tech.
Inhibition Assay
Ki
>20000000±0.0 nM
Citation
 Majamaa, K; Günzler, V; Hanauske-Abel, HM; Myllylä, R; Kivirikko, KI Partial identity of the 2-oxoglutarate and ascorbate binding sites of prolyl 4-hydroxylase. J Biol Chem 261:7819-23 (1986) [PubMed] 
Target
Name:
Prolyl 4-hydroxylase subunit alpha-1
Synonyms:
P4HA | P4HA1 | P4HA1_CHICK | Procollagen-proline,2-oxoglutarate-4-dioxygenase | Prolyl 4-hydroxylase subunit alpha-1
Type:
Protein
Mol. Mass.:
59433.79
Organism:
Chicken
Description:
P16924
Residue:
516
Sequence:
HTDFFTSIGHMTDLINTEKDLVISKLKDYIKAEESKLEQIKKWAEKLDKLTDTATKDPEGFLGHPANAFKLMKRLNTEWGELESLVLKDMSDGFISNMTIQRQFFPNDEDQTGARKALLRLQDTYNLDTDTLSRGNLPGVKHKSFLTAEDCFELGKIRYTEADYYHTELWMEQALKQLDEGEVSSADKVYILDYLSYAVYQQGDLSKAMMLTKRLLELDPEHQRANGNMKYFEYIMAKEKEANKSSTDAEDQTDKETEVKKKDYLPERRKYEMLCRGEGLKMTPRRQKRLFCRYYDGNRNPRYILGPVKQEDEWDKPRIVRFLDIISDEEIETVKELAKPRLSRATVHDPETGKLTTAHYRVSKSAWLSGYESPVVSRINTRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFGRKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFPSGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE
  
Inhibitor
Name:
BDBM92715
Synonyms:
(+)-Mandelate, XXI | (-)-Mandelate, XX
Type:
Small molecule
Emp. Form.:
C8H8O3
Mol. Mass.:
152.1473
SMILES:
OC(C(O)=O)c1ccccc1
Structure:
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