Reaction Details Report a problem with these data
Target
Tyrosine-protein kinase HCK
Ligand
BDBM93207
Substrate
n/a
Meas. Tech.
Fluorescence Assay
pH
7.5000±0.0000
Temperature
298.1500±0.0000 K
IC50
<0.5±0.0 nM
Citation
 Brigham, JL; Perera, BG; Maly, DJ A Hexylchloride-Based Catch-and-Release System for Chemical Proteomic Applications. ACS Chem Biol 8:691-9 (2013) [PubMed]  Article 
Target
Name:
Tyrosine-protein kinase HCK
Synonyms:
Hematopoietic cell kinase | Hemopoietic cell kinase | p59-HCK/p60-HCK | p59Hck | p61Hck | HCK_HUMAN | HCK
Type:
Enzyme Catalytic Domain
Mol. Mass.:
59600.18
Organism:
Human
Description:
P08631
Residue:
526
Sequence:
MGGRSSCEDPGCPRDEERAPRMGCMKSKFLQVGGNTFSKTETSASPHCPVYVPDPTSTIKPGPNSHNSNTPGIREAGSEDIIVVALYDYEAIHHEDLSFQKGDQMVVLEESGEWWKARSLATRKEGYIPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQKLSVPCMSSKPQKPWEKDAWEIPRESLKLEKKLGAGQFGEVWMATYNKHTKVAVKTMKPGSMSVEAFLAEANVMKTLQHDKLVKLHAVVTKEPIYIITEFMAKGSLLDFLKSDEGSKQPLPKLIDFSAQIAEGMAFIEQRNYIHRDLRAANILVSASLVCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGSFTIKSDVWSFGILLMEIVTYGRIPYPGMSNPEVIRALERGYRMPRPENCPEELYNIMMRCWKNRPEERPTFEYIQSVLDDFYTATESQYQQQP
  
Inhibitor
Name:
BDBM93207
Synonyms:
Kinase inhibitor, 5
Type:
Small molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: