Reaction Details Report a problem with these data
Target
Protein Wnt-3a
Ligand
BDBM89440
Substrate
n/a
IC50
2740±n/a nM
Citation
 PubChem, PC Dose response validation of uHTS Gli-SUFU antagonist hits in a Wnt3a luminescent reporter assay PubChem Bioassay (2012)[AID] 
Target
Name:
Protein Wnt-3a
Synonyms:
WNT3A_MOUSE | Wnt-3a | Wnt3a | protein Wnt-3a precursor
Type:
PROTEIN
Mol. Mass.:
39269.29
Organism:
Mus musculus
Description:
ChEMBL_813156
Residue:
352
Sequence:
MAPLGYLLVLCSLKQALGSYPIWWSLAVGPQYSSLSTQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGVKAGIQECQHQFRGRRWNCTTVSNSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGSAAICGCSSRLQGSPGEGWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASEMVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARTERRREKCHCVFHWCCYVSCQECTRVYDVHTCK
  
Inhibitor
Name:
BDBM89440
Synonyms:
4-(4-chlorophenyl)butyl-diethyl-heptyl-ammonium;tosylate | 4-(4-chlorophenyl)butyl-diethyl-heptyl-azanium;4-methylbenzenesulfonate | 4-(4-chlorophenyl)butyl-diethyl-heptylammonium;4-methylbenzenesulfonate | 4-(4-chlorophenyl)butyl-diethyl-heptylazanium;4-methylbenzenesulfonate | CHEMBL9484 | Clofilium tosylate | MLS002154263 | SMR001233522 | cid_175533
Type:
Small organic molecule
Emp. Form.:
C21H37ClN
Mol. Mass.:
338.978
SMILES:
CCCCCCC[N+](CC)(CC)CCCCc1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: