Reaction Details Report a problem with these data
Target
Galanin receptor type 3
Ligand
BDBM97075
Substrate
n/a
IC50
3848±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). PubChem Bioassay (2013)[AID]  BDB Entry
Target
Name:
Galanin receptor type 3
Synonyms:
GALR3 | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39599.97
Organism:
Homo sapiens (Human)
Description:
Galanin R3 GALR3 HUMAN::O60755
Residue:
368
Sequence:
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
  
Inhibitor
Name:
BDBM97075
Synonyms:
4-[1-(2,4-dichlorobenzyl)-3-phenyl-pyrazol-4-yl]-5-keto-2-methyl-4,6,7,8-tetrahydro-1H-quinoline-3-carboxylic acid methyl ester | 4-[1-[(2,4-dichlorophenyl)methyl]-3-phenyl-4-pyrazolyl]-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxylic acid methyl ester | MLS000324781 | SMR000159821 | cid_3380750 | methyl 4-[1-(2,4-dichlorobenzyl)-3-phenyl-1H-pyrazol-4-yl]-2-methyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxylate | methyl 4-[1-[(2,4-dichlorophenyl)methyl]-3-phenyl-pyrazol-4-yl]-2-methyl-5-oxidanylidene-4,6,7,8-tetrahydro-1H-quinoline-3-carboxylate | methyl 4-[1-[(2,4-dichlorophenyl)methyl]-3-phenylpyrazol-4-yl]-2-methyl-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C28H25Cl2N3O3
Mol. Mass.:
522.422
SMILES:
COC(=O)C1=C(C)N=C2CCCC(=O)C2C1c1cn(Cc2ccc(Cl)cc2Cl)nc1-c1ccccc1 |c:4,t:7|
Structure:
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