Reaction Details Report a problem with these data
Target
Galanin receptor type 3
Ligand
BDBM97152
Substrate
n/a
IC50
3556±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3). PubChem Bioassay (2013)[AID] 
Target
Name:
Galanin receptor type 3
Synonyms:
GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39599.97
Organism:
Homo sapiens (Human)
Description:
Galanin R3 GALR3 HUMAN::O60755
Residue:
368
Sequence:
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
  
Inhibitor
Name:
BDBM97152
Synonyms:
1-(3-fluoro-4-methoxy-benzyl)-N-(6-phenoxy-3-pyridyl)isonipecotamide | 1-[(3-fluoranyl-4-methoxy-phenyl)methyl]-N-(6-phenoxypyridin-3-yl)piperidine-4-carboxamide | 1-[(3-fluoro-4-methoxyphenyl)methyl]-N-(6-phenoxy-3-pyridinyl)-4-piperidinecarboxamide | 1-[(3-fluoro-4-methoxyphenyl)methyl]-N-(6-phenoxypyridin-3-yl)piperidine-4-carboxamide | MLS001100829 | SMR000669993 | cid_24819426
Type:
Small organic molecule
Emp. Form.:
C25H26FN3O3
Mol. Mass.:
435.4906
SMILES:
COc1ccc(CN2CCC(CC2)C(=O)Nc2ccc(Oc3ccccc3)nc2)cc1F
Structure:
Search PDB for entries with ligand similarity: