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Target
Mu-type opioid receptor
Ligand
BDBM81195
Substrate
n/a
Meas. Tech.
Late stage Counterscreen for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A)
EC50
92470±n/a nM
Citation
 PubChem, PC Late stage Counterscreen for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay to identify agonists of the mu 1 opioid receptor (OPRM1) PubChem Bioassay (2013)[AID] 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM81195
Synonyms:
(+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide | 2-aminotetralin-6,7-diol;hydrobromide | 6-Amino-5,6,7,8-tetrahydro-naphthalene-2,3-diol | 6-amino-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide | 6-azanyl-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide | ADTN | ADTN, (+) | CA inhibitor, 3 | CHEMBL26736 | MLS002172466 | SMR001254097 | cid_11957526 | cid_3153
Type:
Small organic molecule
Emp. Form.:
C10H13NO2
Mol. Mass.:
179.2157
SMILES:
NC1CCc2cc(O)c(O)cc2C1
Structure:
Search PDB for entries with ligand similarity: