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Target
RAC-beta serine/threonine-protein kinase
Ligand
BDBM145958
Substrate
n/a
Meas. Tech.
TR-FRET Assay
pH
7.5000±n/a
IC50
4±n/a nM
Comments
extracted
Citation
 Vennemann, M; Bär, T; Maier, T; Hölder, S; Beneke, G; Dehmel, F; Zülch, A; Strub, A; Beckers, T; Ince, S; Rehwinkel, H; Liu, N; Bömer, U Fused pyrimidines US Patent  US8957064 Publication Date 2/17/2015 
Target
Name:
RAC-beta serine/threonine-protein kinase
Synonyms:
Serine/threonine-protein kinase AKT | RAC-PK-beta | Protein kinase Akt-2 | Protein kinase B beta (AKT2) | RAC-alpha serine/threonine-protein kinase (AKT2) | RAC-beta serine/threonine-protein kinase | Protein kinase B, beta | PKB beta | Protein kinase B (Akt 2) | RAC-beta serine/threonine-protein kinase (AKT2) | Serine/threonine-protein kinase Rac alpha/beta | Serine/threonine-protein kinase AKT2 | AKT2_HUMAN | AKT2
Type:
Enzyme
Mol. Mass.:
55766.64
Organism:
Human
Description:
n/a
Residue:
481
Sequence:
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRAPGEDPMDYKCGSPSDSSTTEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGLLELDQRTHFPQFSYSASIRE
  
Inhibitor
Name:
BDBM145958
Synonyms:
US8957064, 72.4
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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