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Target
MBT domain-containing protein 1
Ligand
BDBM154565
Substrate
n/a
Meas. Tech.
AlphaScreen Assay
pH
8.0000±0.0000
Temperature
844.4500±0.0000 K
IC50
>1.00e+5±n/a nM
Citation
 Perfetti, MT; Baughman, BM; Dickson, BM; Mu, Y; Cui, G; Mader, P; Dong, A; Norris, JL; Rothbart, SB; Strahl, BD; Brown, PJ; Janzen, WP; Arrowsmith, CH; Mer, G; McBride, KM; James, LI; Frye, SV Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1. ACS Chem Biol 10:1072-81 (2015) [PubMed]  Article 
Target
Name:
MBT domain-containing protein 1
Synonyms:
MBT domain-containing protein 1 | MBTD1_HUMAN | MBTD1 | MBT domain-containing protein 1 (MBTD1)
Type:
Protein
Mol. Mass.:
70557.67
Organism:
Human
Description:
n/a
Residue:
628
Sequence:
MFDGYDSCSEDTSSSSSSEESEEEVAPLPSNLPIIKNNGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLQKQPLVAKLAAYAQYQATLQNQAKTKAAVSMEGFSWGNYINSNSFIAAPVTCFKHAPMGTCWGDISENVRVEVPNTDCSLPTKVFWIAGIVKLAGYNALLRYEGFENDSGLDFWCNICGSDIHPVGWCAASGKPLVPPRTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFKPCMRVEVVDKRHLCRTRVAVVESVIGGRLRLVYEESEDRTDDFWCHMHSPLIHHIGWSRSIGHRFKRSDITKKQDGHFDTPPHLFAKVKEVDQSGEWFKEGMKLEAIDPLNLSTICVATIRKVLADGFLMIGIDGSEAADGSDWFCYHATSPSIFPVGFCEINMIELTPPRGYTKLPFKWFDYLRETGSIAAPVKLFNKDVPNHGFRVGMKLEAVDLMEPRLICVATVTRIIHRLLRIHFDGWEEEYDQWVDCESPDLYPVGWCQLTGYQLQPPASQSSRENQSASSKQKKKAKSQQYKGHKKMTTLQLKEELLDGEDYNFLQGASDQESNGSANFYIKQEP
  
Inhibitor
Name:
BDBM154565
Synonyms:
N-(3-(Tert-butylamino)propyl)-3-(trifluoromethyl)benzamide (21)
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: