Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1B
Ligand
BDBM186934
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
pH
7.4±n/a
Ki
7765±n/a nM
Comments
extracted
Citation
 Besnard, J; Hopkins, AL; Gilbert, I; Ruda, GF; Abecassis, K Morpholino compounds, uses and methods US Patent  US9079895 Publication Date 7/14/2015 
Target
Name:
5-hydroxytryptamine receptor 1B
Synonyms:
5-HT1B | 5-hydroxytryptamine receptor 1B (5HT1B) | 5HT1B_MOUSE | 5ht1b | Htr1b
Type:
Enzyme
Mol. Mass.:
43090.29
Organism:
Mus musculus (Mouse)
Description:
P28334
Residue:
386
Sequence:
MEEQGIQCAPPPPAASQTGVPLTNLSHNCSADGYIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVEYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEMLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRAPDVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCAG
  
Inhibitor
Name:
BDBM186934
Synonyms:
US9079895, 22s
Type:
Small organic molecule
Emp. Form.:
C21H23ClN2O3
Mol. Mass.:
386.872
SMILES:
Clc1cccc(OC[C@@H]2CN(CC(=O)N3CCc4ccccc34)CCO2)c1 |r|
Structure:
Search PDB for entries with ligand similarity: