Reaction Details
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D(3) dopamine receptor
Ligand
BDBM186927
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
pH
7.4±n/a
Ki
2827±n/a nM
Comments
extracted
Citation
Besnard, J; Hopkins, AL; Gilbert, I; Ruda, GF; Abecassis, K Morpholino compounds, uses and methods US Patent US9079895 Publication Date 7/14/2015 More Info.:
Target
Name:
D(3) dopamine receptor
Synonyms:
DRD3_MOUSE | Dopamine D3 receptor | Drd3
Type:
Enzyme
Mol. Mass.:
49693.78
Organism:
Mus musculus (Mouse)
Description:
P30728
Residue:
446
Sequence:
MAPLSQISSHINSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSICSISNPDFVIYSSVVSFYVPFGVTVLVYARIYMVLRQRRRKRILTRQNSQCISIRPGFPQQSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKPYPQKCQDPLLSHLQPLSPGQTHGELKRYYSICQDTALRHPNFEGGGGMSQVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
Inhibitor
Name:
BDBM186927
Synonyms:
US9079895, 19s
Type:
Small organic molecule
Emp. Form.:
C21H26N2O2
Mol. Mass.:
338.4433
SMILES:
C(CN1CCO[C@H](COc2ccccc2)C1)N1CCc2ccccc12 |r|
Structure:
