Reaction Details Report a problem with these data
Target
Serum paraoxonase/arylesterase 1
Ligand
BDBM50001839
Substrate
n/a
Meas. Tech.
Paraoxonase Activity Assay
pH
10.5000±n/a
Ki
1.65e+4± 1.1e+4 nM
IC50
4.2e+4±n/a nM
Comments
extracted
Citation
 Alim, Z; Beydemir, S Some Anticancer Agents Act on Human Serum Paraoxonase-1 to Reduce Its Activity. Chem Biol Drug Des 88:188-96 (2016) [PubMed]  Article 
Target
Name:
Serum paraoxonase/arylesterase 1
Synonyms:
K-45 | Paraoxonase (hPON1) | A-esterase 1 | Aromatic esterase 1 | Serum paraoxonase 1 (PON1) | Serum aryldialkylphosphatase 1 | Paraoxonase 1 (PON1) | PON 1 | Paraoxonase (PON1) | PON1_HUMAN | PON1 | PON
Type:
Enzyme
Mol. Mass.:
39719.73
Organism:
Human
Description:
P27169
Residue:
355
Sequence:
MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPNGLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTFTDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYGTNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAELLAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPPASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL
  
Inhibitor
Name:
BDBM50001839
Synonyms:
CHEMBL428647 | taxol | PACLITAXEL
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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